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Recombinant Human Inorganic pyrophosphatase (PPA1), partial

Recombinant Human Inorganic pyrophosphatase (PPA1), partial — Catalyzes the hydrolysis of inorganic diphosphate into two phosphate molecules. Purity >90%.

SKU: BCRECP-001422 Categories: ,

Product Specifications

Product SkuBCRECP-001422
Product DescriptionRecombinant Human Inorganic pyrophosphatase (PPA1) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 228-289aa. [Accession | Q15181].
Uniprot No.Q15181
Gene NamesPPA1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region228-289aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight10.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Catalyzes the hydrolysis of inorganic diphosphate into two phosphate molecules. Has MAP kinase serine/threonine phosphatase activity toward c-Jun N-terminal kinase (JNK) and, in neuronal cells, is involved in the negative regulation of neurite growth via JNK dephosphorylation.

Biological Context

Subcellular Location: Cytoplasm
Tissue Specificity: Expressed ubiquitously

Product Specifications

Recombinant Human Inorganic pyrophosphatase (PPA1), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 228-289aa, with N-terminal 6xHis-tagged tag, molecular weight 10.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Catalyzes the hydrolysis of inorganic diphosphate into two phosphate molecules (PubMed:33036755, PubMed:38428647). Has MAP kinase serine/threonine phosphatase activity toward c-Jun N-terminal kinase (JNK) and, in neuronal cells, is involved in the negative regulation of neurite growth via JNK dephosphorylation (By similarity)

Subcellular Location

Cytoplasm

Tissue Specificity

Expressed ubiquitously

Subunit

Monomer (PubMed:33036755). Homodimer (PubMed:33036755, PubMed:33583053)

Gene: PPA1  |  Organism: Homo sapiens  |  Synonyms: Pyrophosphate phospho-hydrolase
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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