Recombinant Human Interleukin-12 receptor subunit beta-1 (IL12RB1), partial, Homo sapiens (Human), E.coli, C-terminal hFc1-Avi-tagged, 85.5kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Human Interleukin-12 receptor subunit beta-1 (IL12RB1), partial

Recombinant Human Interleukin-12 receptor subunit beta-1 (IL12RB1), partial — Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Purity >85%.

SKU: BCRECP-000933 Categories: , ,
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Product Specifications

Product SkuBCRECP-000933
Product DescriptionRecombinant Human Interleukin-12 receptor subunit beta-1 (IL12RB1) Protein is expressed from E.coli with C-terminal hFc1-Avi-tagged. It contains 24-545aa. [Accession | P42701].
Uniprot No.P42701
Gene NamesIL12RB1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region24-545aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-Avi-tagged
Molecular weight85.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Also associates with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Product Specifications

Recombinant Human Interleukin-12 receptor subunit beta-1 (IL12RB1), partial is a recombinant protein, expressed in E.coli, covering amino acids 24-545aa, with C-terminal hFc1-Avi-tagged tag, molecular weight 85.5kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Also associates with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade

Gene: IL12RB1  |  Organism: Homo sapiens

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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