Product Specifications
| Catalog Number | BIC-0724E |
|---|---|
| Target | Interleukin-23 (p19/p40 heterodimer) |
| Target Symbol | IL23A / IL12B |
| Species | Human |
| Expression System | CHO |
| Expression Region | Recombinant human IL-23 is composed of P40 (Ile23-Ser328) and P19 (Arg23-Pro189) subunits, which linked by GS-linker(GSGSSRGGSGSGGSGGGGSKL). |
| Molecular Weight | 55.0 kDa (IL-23 single chain); 36.5 kDa (p40) & 18.5 kDa (p19) |
| Purity | ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Formulation | Lyophilized |
| Buffer | Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH 7.4. |
| Reconstitution | It is recommended to redissolve in sterile deionized water. |
| Storage & Stability | 36 months at-20°C to-80°C in lyophilized state; 6 months at -20°C to -80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipping | The product is shipped with blue ice. |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Accession | P29460(P40), AAG37232(P19) |
| Alternative Names | IL-23 p19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF |
Bioactivity
Measured by its ability to enhance IFN-gamma secretion in NK-92 human natural killer lymphoma cells.
Quality Data
Recombinant Human IL-23 (Cat. No. BIC-0724E) was analyzed by SDS-PAGE.
