Recombinant Human Islet amyloid polypeptide (IAPP), partial, Homo sapiens (Human), Yeast, N-terminal 6xHis-tagged, 5.9kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Islet amyloid polypeptide (IAPP), partial

Recombinant Human Islet amyloid polypeptide (IAPP), partial — Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Purity >90%.

SKU: BCRECP-000877 Category:
Online Inquiry →

Product Specifications

Product SkuBCRECP-000877
Product DescriptionRecombinant Human Islet amyloid polypeptide (IAPP) Protein is expressed from Yeast with N-terminal 6xHis-tagged. It contains 34-70aa. [Accession | P10997].
Uniprot No.P10997
Gene NamesIAPP
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region34-70aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight5.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Human Islet amyloid polypeptide (IAPP), partial is a recombinant protein from Homo sapiens (Human), expressed in Yeast, covering amino acids 34-70aa, with N-terminal 6xHis-tagged tag, molecular weight 5.9kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis (PubMed:2690069). Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes (By similarity). Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs (By similarity)

Subcellular Location

Secreted

Subunit

Can form homodimers (PubMed:19475663). Interacts with IDE and INS (PubMed:17051221, PubMed:19475663). Interaction with INS inhibits homodimerization and fibril formation (PubMed:19475663)

Gene: IAPP  |  Organism: Homo sapiens  |  Synonyms: Amylin; Diabetes-associated peptide; Insulinoma amyloid peptide
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top