Recombinant Human Lipopolysaccharide-binding protein (LBP), partial, Homo sapiens (Human), E.coli, N-terminal 10xHis-GST-tagged and C-terminal Myc-tagged, 47.4kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Lipopolysaccharide-binding protein (LBP), partial

Recombinant Human Lipopolysaccharide-binding protein (LBP), partial — Plays a role in the innate immune response. Purity >85%.

SKU: BCRECP-001052 Category:
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Product Specifications

Product SkuBCRECP-001052
Product DescriptionRecombinant Human Lipopolysaccharide-binding protein (LBP) Protein is expressed from E.coli with N-terminal 10xHis-GST-tagged and C-terminal Myc-tagged. It contains 304-414aa. [Accession | P18428].
Uniprot No.P18428
Gene NamesLBP
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region304-414aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-GST-tagged and C-terminal Myc-tagged
Molecular weight47.4kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS.

Biological Context

Subcellular Location: Secreted; Cytoplasmic granule membrane
Tissue Specificity: Detected in blood serum (at protein level)

Product Specifications

Recombinant Human Lipopolysaccharide-binding protein (LBP), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 304-414aa, with N-terminal 10xHis-GST-tagged and C-terminal Myc-tagged tag, molecular weight 47.4kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria (PubMed:24120359, PubMed:7517398). Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:24120359, PubMed:7517398)

Subcellular Location

Secreted; Cytoplasmic granule membrane

Tissue Specificity

Detected in blood serum (at protein level)

Subunit

When bound to LPS, interacts (via C-terminus) with soluble and membrane-bound CD14

Gene: LBP  |  Organism: Homo sapiens
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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