Recombinant Human Low-density lipoprotein receptor (LDLR), partial, Homo sapiens (Human), Mammalian cell, Tag type will be determined during the manufacturing process. The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially., 89.2 kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Low-density lipoprotein receptor (LDLR), partial

Recombinant Human Low-density lipoprotein receptor (LDLR), partial — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >90%.

SKU: BCACP-000110 Category:
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Product SKUBCACP-000110
Product DescriptionRecombinant Human Low-density lipoprotein receptor (LDLR) protein is expressed from Mammalian cell with Tag type will be determined during the manufacturing process. The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.. It contains 22-788aa. [Accession | P01130].
Uniprot No.P01130
Gene NamesLDLR
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region22-788aa
SpeciesHomo sapiens (Human)
Tag InfoTag type will be determined during the manufacturing process. The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Molecular weight89.2 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized CD30 at 5 μg/ml can bind human CD30L, the EC50 is 4.169-6.360 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesLDL receptor

Function

(Microbial infection) Acts as a receptor for many Alphavirus, including Getah virus (GETV), Ross river virus (RRV) and Semliki Forest virus.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein); Membrane, clathrin-coated pit; Golgi apparatus; Early endosome; Late endosome; Lysosome
Disease Association: Hypercholesterolemia, familial, 1 (FHCL1) : A form of hypercholesterolemia, a disorder of lipoprotein metabolism characterized by elevated serum low-density lipoprotein (LDL) cholesterol levels, which result in excess deposition of cholesterol in tissues and leads to xanthelasma, xanthomas, accelerated atherosclerosis and increased risk of premature coronary heart disease. FHCL1 inheritance is autosomal dominant. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Low-density lipoprotein receptor (LDLR), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 22-788aa, with Tag type will be determined during the manufacturing process. The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. tag, molecular weight 89.2 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized CD30 at 5 μg/ml can bind human CD30L, the EC50 is 4.169-6.360 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Acts as a receptor for many Alphavirus, including Getah virus (GETV), Ross river virus (RRV) and Semliki Forest virus

Subcellular Location

Cell membrane (Single-pass type I membrane protein); Membrane, clathrin-coated pit; Golgi apparatus; Early endosome; Late endosome; Lysosome

Disease Association

Hypercholesterolemia, familial, 1 (FHCL1) : A form of hypercholesterolemia, a disorder of lipoprotein metabolism characterized by elevated serum low-density lipoprotein (LDL) cholesterol levels, which result in excess deposition of cholesterol in tissues and leads to xanthelasma, xanthomas, accelerated atherosclerosis and increased risk of premature coronary heart disease. FHCL1 inheritance is autosomal dominant. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

(Microbial infection) May interact with HIV-1 Tat

Gene: LDLR  |  Organism: Homo sapiens

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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