Recombinant Human Lymphocyte antigen 6E (LY6E) (Active), Homo sapiens (Human), Mammalian cell, N-terminal hFc-tagged, 34.6kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Lymphocyte antigen 6E (LY6E) (Active)

Recombinant Human Lymphocyte antigen 6E (LY6E) (Active) — (Microbial infection) Promotes entry, likely through an enhanced virus-cell fusion process, of various viruses including HIV-1, West Nile virus, dengue virus and Zika virus. Purity >95%.

SKU: BCRECP-001091 Category:
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Product Specifications

Product SkuBCRECP-001091
Product DescriptionRecombinant Human Lymphocyte antigen 6E (LY6E) (Active) Protein is expressed from Mammalian cell with N-terminal hFc-tagged. It contains 21-101aa. [Accession | Q16553].
Uniprot No.Q16553
Gene NamesLY6E
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region21-101aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal hFc-tagged
Molecular weight34.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Biology

Function

(Microbial infection) Promotes entry, likely through an enhanced virus-cell fusion process, of various viruses including HIV-1, West Nile virus, dengue virus and Zika virus. In contrast, the paramyxovirus PIV5, which enters at the plasma membrane, does not require LY6E. Mechanistically, adopts a microtubule-like organization upon viral infection and enhances viral uncoating after endosomal escape.

Biological Context

Subcellular Location: Cell membrane (Lipid-anchor, GPI-anchor)
Tissue Specificity: Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes

Product Specifications

Recombinant Human Lymphocyte antigen 6E (LY6E) (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 21-101aa, with N-terminal hFc-tagged tag, molecular weight 34.6kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

(Microbial infection) Promotes entry, likely through an enhanced virus-cell fusion process, of various viruses including HIV-1, West Nile virus, dengue virus and Zika virus (PubMed:28130445). In contrast, the paramyxovirus PIV5, which enters at the plasma membrane, does not require LY6E (PubMed:28130445, PubMed:29610346). Mechanistically, adopts a microtubule-like organization upon viral infection and enhances viral uncoating after endosomal escape (PubMed:28130445, PubMed:30190477)

Subcellular Location

Cell membrane (Lipid-anchor, GPI-anchor)

Tissue Specificity

Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes

Subunit

Interacts with CHRNA4

Gene: LY6E  |  Organism: Homo sapiens  |  Synonyms: Retinoic acid-induced gene E protein; Stem cell antigen 2; Thymic shared antigen 1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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