Recombinant Human Metalloproteinase inhibitor 2 (TIMP2), Homo sapiens (Human), Mammalian cell, C-terminal 6xHis-myc-tagged, 25.1kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Metalloproteinase inhibitor 2 (TIMP2)

Recombinant Human Metalloproteinase inhibitor 2 (TIMP2) — Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Purity >90%.

SKU: BCRECP-001777 Category:
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Product Specifications

Product SkuBCRECP-001777
Product DescriptionRecombinant Human Metalloproteinase inhibitor 2 (TIMP2) Protein is expressed from Mammalian cell with C-terminal 6xHis-myc-tagged. It contains 27-220aa. [Accession | P16035].
Uniprot No.P16035
Gene NamesTIMP2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region27-220aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-myc-tagged
Molecular weight25.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Human Metalloproteinase inhibitor 2 (TIMP2) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 27-220aa, with C-terminal 6xHis-myc-tagged tag, molecular weight 25.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19

Subcellular Location

Secreted

Subunit

Interacts (via the C-terminal) with MMP2 (via the C-terminal PEX domain); the interaction inhibits the MMP2 activity

Gene: TIMP2  |  Organism: Homo sapiens  |  Synonyms: CSC-21K; Tissue inhibitor of metalloproteinases 2
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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