Recombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17), Homo sapiens (Human), E.coli, C-terminal 6xHis-tagged, 55.6kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17)

Recombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17) — Mitochondrial ribosome (mitoribosome) assembly factor. Purity >90%.

SKU: BCRECP-001156 Categories: ,
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Product Specifications

Product SkuBCRECP-001156
Product DescriptionRecombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 20-456aa. [Accession | Q9H7H0].
Uniprot No.Q9H7H0
Gene NamesMETTL17
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region20-456aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight55.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.

Biological Context

Subcellular Location: Mitochondrion matrix

Product Specifications

Recombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 20-456aa, with C-terminal 6xHis-tagged tag, molecular weight 55.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Mitochondrial ribosome (mitoribosome) assembly factor (PubMed:36482135, PubMed:38199006). Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body (PubMed:36482135). Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity (PubMed:38234605)

Subcellular Location

Mitochondrion matrix

Subunit

Associates with the mitochondrial ribosome (mitoribosome)

Gene: METTL17  |  Organism: Homo sapiens  |  Synonyms: False p73 target gene protein; Methyltransferase 11 domain-containing protein 1; Methyltransferase-like protein 17; Protein RSM22 homolog, mitochondrial
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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