Recombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17), Homo sapiens (Human), E.coli, C-terminal 6xHis-tagged, 55.6kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17)

Recombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17) — Mitochondrial ribosome (mitoribosome) assembly factor. Purity >90%.

SKU: BCRECP-001156 Categories: ,
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Product Specifications

Product SkuBCRECP-001156
Product DescriptionRecombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 20-456aa. [Accession | Q9H7H0].
Uniprot No.Q9H7H0
Gene NamesMETTL17
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region20-456aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight55.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.

Biological Context

Subcellular Location: Mitochondrion matrix

Product Specifications

Recombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 20-456aa, with C-terminal 6xHis-tagged tag, molecular weight 55.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Mitochondrial ribosome (mitoribosome) assembly factor (PubMed:36482135, PubMed:38199006). Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body (PubMed:36482135). Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity (PubMed:38234605)

Subcellular Location

Mitochondrion matrix

Subunit

Associates with the mitochondrial ribosome (mitoribosome)

Gene: METTL17  |  Organism: Homo sapiens  |  Synonyms: False p73 target gene protein; Methyltransferase 11 domain-containing protein 1; Methyltransferase-like protein 17; Protein RSM22 homolog, mitochondrial
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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