Recombinant Human Mitochondrial thiamine pyrophosphate carrier (SLC25A19) Protein, Homo sapiens (Human), in vitro E.coli expression system, N-terminal 10xHis-tagged, 37.0kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Mitochondrial thiamine pyrophosphate carrier (SLC25A19) Protein

Recombinant Human Mitochondrial thiamine pyrophosphate carrier (SLC25A19) Protein — Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria. Purity >85%.

SKU: BCRECP-00220TM Category:
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Product Specifications

Uniprot No.Q9HC21
Gene NamesSLC25A19
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region1-320aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight37.0kDa
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria. It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient.

Biological Context

Subcellular Location: Mitochondrion membrane (Multi-pass membrane protein)
Tissue Specificity: Expressed in all tissues examined except for placenta. Highest levels in colon, kidney, lung, testis, spleen, and brain
Disease Association: Microcephaly, Amish type (MCPHA) : A disorder characterized by severe congenital microcephaly and severe 2-ketoglutaric aciduria leading to death within the first year. [The disease is caused by variants affecting the gene represented in this entry] | Thiamine metabolism dysfunction syndrome 4, bilateral striatal degeneration and progressive polyneuropathy type (THMD4) : A disease characterized by recurrent episodes of flaccid paralysis and encephalopathy associated with bilateral striatal necrosis and chronic progressive polyneuropathy. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Mitochondrial thiamine pyrophosphate carrier (SLC25A19) Protein is a recombinant protein from Homo sapiens (Human), expressed in in vitro E.coli expression system, covering amino acids 1-320aa, with N-terminal 10xHis-tagged tag, molecular weight 37.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria. It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient

Subcellular Location

Mitochondrion membrane (Multi-pass membrane protein)

Disease Association

Microcephaly, Amish type (MCPHA) : A disorder characterized by severe congenital microcephaly and severe 2-ketoglutaric aciduria leading to death within the first year. [The disease is caused by variants affecting the gene represented in this entry] | Thiamine metabolism dysfunction syndrome 4, bilateral striatal degeneration and progressive polyneuropathy type (THMD4) : A disease characterized by recurrent episodes of flaccid paralysis and encephalopathy associated with bilateral striatal necrosis and chronic progressive polyneuropathy. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Expressed in all tissues examined except for placenta. Highest levels in colon, kidney, lung, testis, spleen, and brain

Gene: SLC25A19  |  Organism: Homo sapiens  |  Synonyms: Mitochondrial thiamine pyrophosphate transporter; Mitochondrial uncoupling protein 1; Solute carrier family 25 member 19
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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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