Recombinant Human Myosin regulatory light chain 12B (MYL12B) (Active), Homo sapiens (Human), E.coli, C-terminal 6xHis-tagged, 26.7kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Myosin regulatory light chain 12B (MYL12B) (Active)

Recombinant Human Myosin regulatory light chain 12B (MYL12B) (Active) — Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Purity >95%.

SKU: BCRECP-001210 Category:
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Product Specifications

Product SkuBCRECP-001210
Product DescriptionRecombinant Human Myosin regulatory light chain 12B (MYL12B) (Active) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 1-172aa. [Accession | O14950].
Uniprot No.O14950
Gene NamesMYL12B
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-172aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight26.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion.

Biological Context

Tissue Specificity: Ubiquitously expressed in various hematopoietic cells

Product Specifications

Recombinant Human Myosin regulatory light chain 12B (MYL12B) (Active) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-172aa, with C-terminal 6xHis-tagged tag, molecular weight 26.7kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion

Tissue Specificity

Ubiquitously expressed in various hematopoietic cells

Subunit

Myosin is a hexamer of 2 heavy chains and 4 light chains: interacts with myosin heavy chain MYO19

Gene: MYL12B  |  Organism: Homo sapiens  |  Synonyms: MLC-2A; Myosin regulatory light chain 2-B, smooth muscle isoform; Myosin regulatory light chain 20 kDa; Myosin regulatory light chain MRLC2; SHUJUN-1
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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