Function
Parathyroid hormone elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
Product Specifications
Recombinant Human Parathyroid hormone (PTH) (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 32-115aa, with C-terminal hFc1-tagged tag, molecular weight 38.3 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CSF1R at 2 μg/mL can bind Anti-CSF1R recombinant antibody . The EC50 is 1.800-2.218 ng/mL.;Measured by its binding ability in a functional ELISA. Immobilized Human CSF1R at 2 μg/mL can bind Human CSF1 . The EC50 is 22.53-25.44 ng/mL.
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
