Recombinant Human Peptide YY protein (PYY), partial, Homo sapiens (Human), E.coli, N-terminal GST-tagged, 31.1kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Peptide YY protein (PYY), partial

Recombinant Human Peptide YY protein (PYY), partial — Is a NPY2R agonist involved in the down-regulation of appetite and food intake, probably acting on receptors located on proopiomelanocortin(POMC)-releasing and neuropeptide Y(NPY)-releasing neurons… Purity >90%.

SKU: BCRECP-001495 Category:
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Product Specifications

Product SkuBCRECP-001495
Product DescriptionRecombinant Human Peptide YY protein (PYY) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 31-64aa. [Accession | P10082].
Uniprot No.P10082
Gene NamesPYY
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region31-64aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight31.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasMetabolism

Function

Is a NPY2R agonist involved in the down-regulation of appetite and food intake, probably acting on receptors located on proopiomelanocortin(POMC)-releasing and neuropeptide Y(NPY)-releasing neurons in the arcuate nucleus of hypothalamus. In NPY-releasing neurons, NPY2R activation by PYY(3-36) leads to membrane hyperpolarization and reduced release of the orexigenic neuropeptide NPY.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Human Peptide YY protein (PYY), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 31-64aa, with N-terminal GST-tagged tag, molecular weight 31.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Is a NPY2R agonist involved in the down-regulation of appetite and food intake, probably acting on receptors located on proopiomelanocortin(POMC)-releasing and neuropeptide Y(NPY)-releasing neurons in the arcuate nucleus of hypothalamus (PubMed:12167864). In NPY-releasing neurons, NPY2R activation by PYY(3-36) leads to membrane hyperpolarization and reduced release of the orexigenic neuropeptide NPY (By similarity)

Subcellular Location

Secreted

Gene: PYY  |  Organism: Homo sapiens  |  Synonyms: PYY-I; Peptide tyrosine tyrosine
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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