Recombinant Human Plasminogen activator inhibitor 2 protein (SERPINB2)

Recombinant Human Plasminogen activator inhibitor 2 protein (SERPINB2) — Inhibits urokinase-type plasminogen activator. Purity >95%.

SKU: BCACP-000853 Category:
Product SKUBCACP-000853
Product DescriptionRecombinant Human Plasminogen activator inhibitor 2 protein (SERPINB2) protein is expressed from E.Coli with Tag-Free. It contains 1-415aa. [Accession | P05120].
Uniprot No.P05120
Gene NamesSERPINB2
Purity>95% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region1-415aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight46.6 kDa
ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TT medullary thyroid cancer cells is less than 10 ng/ml, corresponding to a specific activity of >1.0x105 IU/mg.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesHsT1201; Monocyte Arg serpin ; Monocyte Arg-serpin; Monocyte Arginine-serpin; Monocyte-derived plasminogen activator inhibitor; PAI; PAI-2; PAI2 ; PAI2_HUMAN; Placental plasminogen activator inhibitor; PLANH2 ; Plasminogen activator inhibitor 2; plasminogen activator inhibitor; type 2; plasminogen activator inhibitor; type II (arginine-serpin); serine (or cysteine) proteinase inhibitor; clade B (ovalbumin); member 2; Serpin B2; serpin peptidase inhibitor; clade B (ovalbumin); member 2; Serpinb2; Urokinase inhibitor

Function

Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.

Biological Context

Subcellular Location: Cytoplasm; Secreted, extracellular space

Product Specifications

Recombinant Human Plasminogen activator inhibitor 2 protein (SERPINB2) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 1-415aa, with Tag-Free tag, molecular weight 46.6 kDa, purity >95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TT medullary thyroid cancer cells is less than 10 ng/ml, corresponding to a specific activity of >1.0x105 IU/mg.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1

Subcellular Location

Cytoplasm; Secreted, extracellular space

Subunit

Interacts with PSMB1

Gene: SERPINB2  |  Organism: Homo sapiens  |  Synonyms: Monocyte Arg-serpin; Placental plasminogen activator inhibitor; Serpin B2; Urokinase inhibitor
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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