Recombinant Human Pleckstrin homology-like domain family A member 2 (PHLDA2), Homo sapiens (Human), E.coli, N-terminal GST-tagged, 44.1kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Pleckstrin homology-like domain family A member 2 (PHLDA2)

Recombinant Human Pleckstrin homology-like domain family A member 2 (PHLDA2) — Plays a role in regulating placenta growth. Purity >90%.

SKU: BCRECP-001380 Category:
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Product Specifications

Product SkuBCRECP-001380
Product DescriptionRecombinant Human Pleckstrin homology-like domain family A member 2 (PHLDA2) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 1-152aa. [Accession | Q53GA4].
Uniprot No.Q53GA4
Gene NamesPHLDA2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-152aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight44.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Biology

Function

Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids.

Biological Context

Subcellular Location: Cytoplasm; Membrane (Peripheral membrane protein)
Tissue Specificity: Expressed in placenta and adult prostate gland. In placenta, it is present in all cells of the villous cytotrophoblast. The protein is absent in cells from hydatidiform moles. Hydatidiform mole is a gestation characterized by abnormal development of both fetus and trophoblast. The majority of hydatidiform moles are associated with an excess of paternal to maternal genomes and are likely to result from the abnormal expression of imprinted genes (at protein level). Expressed at low levels in adult liver and lung, and fetal liver. Expressed in adult brain and neuroblastoma, medullablastoma and glioblastoma cell lines

Product Specifications

Recombinant Human Pleckstrin homology-like domain family A member 2 (PHLDA2) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-152aa, with N-terminal GST-tagged tag, molecular weight 44.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity)

Subcellular Location

Cytoplasm; Membrane (Peripheral membrane protein)

Tissue Specificity

Expressed in placenta and adult prostate gland. In placenta, it is present in all cells of the villous cytotrophoblast. The protein is absent in cells from hydatidiform moles. Hydatidiform mole is a gestation characterized by abnormal development of both fetus and trophoblast. The majority of hydatidiform moles are associated with an excess of paternal to maternal genomes and are likely to result from the abnormal expression of imprinted genes (at protein level). Expressed at low levels in adult liver and lung, and fetal liver. Expressed in adult brain and neuroblastoma, medullablastoma and glioblastoma cell lines

Gene: PHLDA2  |  Organism: Homo sapiens  |  Synonyms: Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein; Imprinted in placenta and liver protein; Tumor-suppressing STF cDNA 3 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein; p17-Beckwith-Wiedemann region 1 C
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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