Recombinant Human Probetacellulin [Cleaved into: Betacellulin protein (BTC), partial (Active)

Recombinant Human Probetacellulin [Cleaved into: Betacellulin protein (BTC), partial (Active) — Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Purity >98%.

SKU: BCACP-000942 Category:
Product SKUBCACP-000942
Product DescriptionRecombinant Human Probetacellulin [Cleaved into: Betacellulin protein (BTC) protein is expressed from E.Coli with Tag-Free. It contains 32-111aa. [Accession | P35070].
Uniprot No.P35070
Gene NamesBTC
Purity>98% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region32-111aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight9.0 kDa
ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using serum free human MCF-7 cells is less than 40 ng/ml, corresponding to a specific activity of >2.5x104 IU/mg.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesBTCProbetacellulin [Cleaved into: Betacellulin; BTC)]

Function

Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.

Product Specifications

Recombinant Human Probetacellulin [Cleaved into: Betacellulin protein (BTC), partial (Active) is a recombinant protein, expressed in E.Coli, covering amino acids 32-111aa, with Tag-Free tag, molecular weight 9.0 kDa, purity >98% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using serum free human MCF-7 cells is less than 40 ng/ml, corresponding to a specific activity of >2.5x104 IU/mg.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells

Gene: BTC  |  Organism: Homo sapiens

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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