Recombinant Human Programmed cell death 1 ligand 2 (PDCD1LG2), partial, Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 51.6kDa, purity >85% as determined by SDS-PAGE.
,

Recombinant Human Programmed cell death 1 ligand 2 (PDCD1LG2), partial

Recombinant Human Programmed cell death 1 ligand 2 (PDCD1LG2), partial — Plays a critical role in induction and maintenance of immune tolerance to self. Purity >85%.

SKU: BCRECP-001359 Categories: ,
Online Inquiry →

Product Specifications

Product SkuBCRECP-001359
Product DescriptionRecombinant Human Programmed cell death 1 ligand 2 (PDCD1LG2) Protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 20-220aa. [Accession | Q9BQ51].
Uniprot No.Q9BQ51
Gene NamesPDCD1LG2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region20-220aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight51.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein)
Tissue Specificity: Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus

Product Specifications

Recombinant Human Programmed cell death 1 ligand 2 (PDCD1LG2), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 20-220aa, with C-terminal hFc1-tagged tag, molecular weight 51.6kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11224527, PubMed:12538684). Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production (PubMed:11224527)

Subcellular Location

Cell membrane (Single-pass type I membrane protein)

Tissue Specificity

Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus

Gene: PDCD1LG2  |  Organism: Homo sapiens  |  Synonyms: Butyrophilin B7-DC
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top