Recombinant Human Programmed cell death protein 6 (PDCD6), Homo sapiens (Human), E.coli, N-terminal GST-tagged, 49.3kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Programmed cell death protein 6 (PDCD6)

Recombinant Human Programmed cell death protein 6 (PDCD6) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-000060 Categories: ,
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Product Specifications

Product SkuBCRECP-000060
Product DescriptionRecombinant Human Programmed cell death protein 6 (PDCD6) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 1-191aa. [Accession | O75340].
Uniprot No.O75340
Gene NamesALG2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-191aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight49.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasApoptosis

Function

Has a lower Ca(2+) affinity than isoform 1.

Biological Context

Subcellular Location: Endoplasmic reticulum membrane (Peripheral membrane protein); Cytoplasmic vesicle, COPII-coated vesicle membrane; Cytoplasm; Nucleus; Endosome

Product Specifications

Recombinant Human Programmed cell death protein 6 (PDCD6) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-191aa, with N-terminal GST-tagged tag, molecular weight 49.3kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Has a lower Ca(2+) affinity than isoform 1 (By similarity)

Subcellular Location

Endoplasmic reticulum membrane (Peripheral membrane protein); Cytoplasmic vesicle, COPII-coated vesicle membrane; Cytoplasm; Nucleus; Endosome

Subunit

Homodimer and heterodimer; heterodimerizes (via the EF-hand 5) with PEF1 (PubMed:11278427, PubMed:11883899, PubMed:27784779). Isoform 1 and isoform 2 self-associate; probably forming homodimers. Interacts with CPNE4 (via VWFA domain) (By similarity). Interacts with PDCD6IP; the interaction is calcium-dependent (PubMed:16957052, PubMed:18256029, PubMed:18940611, PubMed:20691033, PubMed:25667979). Interacts with RBM22 (PubMed:17045351). Interacts with PLSCR4 (PubMed:18256029). Interacts with ANXA7 and TSG101 (PubMed:18256029, PubMed:20691033). Interacts with DAPK1 (PubMed:16132846). Interacts with SEC31A; the interaction is calcium-dependent and promotes monoubiquitination of SEC31A (PubMed:16957052, PubMed:18256029, PubMed:25667979, PubMed:27716508). Interacts with ANXA11 (via N-terminus); the interaction is calcium-dependent (PubMed:11883939, PubMed:18256029, PubMed:18940611). Interacts with PLSCR3 (via N-terminus); the interaction is calcium-dependent (PubMed:18256029). Interacts with MCOLN1; the interaction is calcium-dependent (PubMed:19864416). Interacts with KDR; the interaction is calcium-dependent (PubMed:21893193). Interacts with HEBP2; the interaction is calcium-dependent (PubMed:27784779). Interacts with TFG (PubMed:27813252). Isoform 1: Interacts with SHISA5, leading to stabilize it (PubMed:17889823). Isoform 2: Does not interact with SHISA5 (PubMed:17889823). Isoform 2: Does not interact with PDCD6IP, TSG101, ANXA7 and ANXA11 (PubMed:18256029, PubMed:20691033)

Gene: PDCD6  |  Organism: Homo sapiens  |  Synonyms: Apoptosis-linked gene 2 protein homolog

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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