Recombinant Human Programmed cell death protein 6 (PDCD6), Homo sapiens (Human), E.coli, N-terminal GST-tagged, 49.3kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Programmed cell death protein 6 (PDCD6)

Recombinant Human Programmed cell death protein 6 (PDCD6) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-000060 Category:
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Product Specifications

Product SkuBCRECP-000060
Product DescriptionRecombinant Human Programmed cell death protein 6 (PDCD6) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 1-191aa. [Accession | O75340].
Uniprot No.O75340
Gene NamesALG2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-191aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight49.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasApoptosis

Function

Has a lower Ca(2+) affinity than isoform 1.

Biological Context

Subcellular Location: Endoplasmic reticulum membrane (Peripheral membrane protein); Cytoplasmic vesicle, COPII-coated vesicle membrane; Cytoplasm; Nucleus; Endosome

Product Specifications

Recombinant Human Programmed cell death protein 6 (PDCD6) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-191aa, with N-terminal GST-tagged tag, molecular weight 49.3kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Has a lower Ca(2+) affinity than isoform 1 (By similarity)

Subcellular Location

Endoplasmic reticulum membrane (Peripheral membrane protein); Cytoplasmic vesicle, COPII-coated vesicle membrane; Cytoplasm; Nucleus; Endosome

Subunit

Homodimer and heterodimer; heterodimerizes (via the EF-hand 5) with PEF1 (PubMed:11278427, PubMed:11883899, PubMed:27784779). Isoform 1 and isoform 2 self-associate; probably forming homodimers. Interacts with CPNE4 (via VWFA domain) (By similarity). Interacts with PDCD6IP; the interaction is calcium-dependent (PubMed:16957052, PubMed:18256029, PubMed:18940611, PubMed:20691033, PubMed:25667979). Interacts with RBM22 (PubMed:17045351). Interacts with PLSCR4 (PubMed:18256029). Interacts with ANXA7 and TSG101 (PubMed:18256029, PubMed:20691033). Interacts with DAPK1 (PubMed:16132846). Interacts with SEC31A; the interaction is calcium-dependent and promotes monoubiquitination of SEC31A (PubMed:16957052, PubMed:18256029, PubMed:25667979, PubMed:27716508). Interacts with ANXA11 (via N-terminus); the interaction is calcium-dependent (PubMed:11883939, PubMed:18256029, PubMed:18940611). Interacts with PLSCR3 (via N-terminus); the interaction is calcium-dependent (PubMed:18256029). Interacts with MCOLN1; the interaction is calcium-dependent (PubMed:19864416). Interacts with KDR; the interaction is calcium-dependent (PubMed:21893193). Interacts with HEBP2; the interaction is calcium-dependent (PubMed:27784779). Interacts with TFG (PubMed:27813252). Isoform 1: Interacts with SHISA5, leading to stabilize it (PubMed:17889823). Isoform 2: Does not interact with SHISA5 (PubMed:17889823). Isoform 2: Does not interact with PDCD6IP, TSG101, ANXA7 and ANXA11 (PubMed:18256029, PubMed:20691033)

Gene: PDCD6  |  Organism: Homo sapiens  |  Synonyms: Apoptosis-linked gene 2 protein homolog

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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