Product Specifications
Recombinant Human Prominin-2 (PROM2), partial — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%. Suitable for ELISA and Western Blot applications.
Recombinant Protein
Recombinant Human Prominin-2 (PROM2), partial
Recombinant Human Prominin-2 (PROM2), partial — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.
Product Specifications
| Product Sku | BCRECP-001448 |
| Product Description | Recombinant Human Prominin-2 (PROM2) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 27-106aa. [Accession | Q8N271]. |
| Uniprot No. | Q8N271 |
| Gene Names | PROM2 |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Expression System | E.coli |
| Expression Region | 27-106aa |
| Species | Homo sapiens (Human) |
| Tag Info | N-terminal 6xHis-SUMO-tagged |
| Molecular weight | 21.8kDa |
| Activity | Please contact us to obtain bioactivity data. |
| Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose. |
| Storage | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| Research Areas | Cancer |
SDS-PAGE: Single band at expected molecular weight confirming purity.
ELISA: Suitable as coating antigen or detection standard.
Western Blot: Compatible with standard Western Blot protocols.
Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.
Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.
Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.
Shelf Life: 12 months from date of receipt when stored as recommended.
Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.
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Protein Biology
Subcellular Location
Apical cell membrane (Multi-pass membrane protein); Basolateral cell membrane (Multi-pass membrane protein); Cell projection, microvillus membrane (Multi-pass membrane protein); Cell projection, cilium membrane (Multi-pass membrane protein)
Tissue Specificity
Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines
Subunit
Binds cholesterol
Gene: PROM2 | Organism: Homo sapiens | Synonyms: Prominin-like protein 2
Key Publications
- Fargeas C.A. et al. Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins. — J. Biol. Chem. (2003)
- Clark H.F. et al. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. — Genome Res. (2003)
- Ota T. et al. Complete sequencing and characterization of 21,243 full-length human cDNAs. — Nat. Genet. (2004)
- Hillier L.W. et al. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. — Nature (2005)
- Mural R.J. et al. PubMed: CI-5GBDQ6B103N1E (JUL-)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). — Genome Res. (2004)
- Zhang Q. et al. Identification and characterization of a novel testosterone-regulated prominin-like gene in the rat ventral prostate. — Endocrinology (2002)
- Mori T. et al. An ultrastructural and immunohistochemical study of a combined submucosal granular cell tumor and lipoma of the colon showing a unique nodule-in-nodule structure: putative implication of CD34 or prominin-2-positive stromal cells in its histopathogenesis. — Virchows Arch. (2006)
Frequently Asked Questions
How do I order or inquire about this product?
Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.
What is the shipping and delivery time?
Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.
How should I store this recombinant protein?
Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.
What quality controls are performed on your products?
Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.