Product Specifications
Recombinant Human Prominin-2 (PROM2), partial — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%. Suitable for ELISA and Western Blot applications.
Recombinant Proteins for Research
Recombinant Human Prominin-2 (PROM2), partial
Recombinant Human Prominin-2 (PROM2), partial — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.
Product Specifications
| Product Sku | BCRECP-001448 |
| Product Description | Recombinant Human Prominin-2 (PROM2) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 27-106aa. [Accession | Q8N271]. |
| Uniprot No. | Q8N271 |
| Gene Names | PROM2 |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Expression System | E.coli |
| Expression Region | 27-106aa |
| Species | Homo sapiens (Human) |
| Tag Info | N-terminal 6xHis-SUMO-tagged |
| Molecular weight | 21.8kDa |
| Activity | Please contact us to obtain bioactivity data. |
| Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose. |
| Storage | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| Research Areas | Cancer |
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Please contact us to obtain bioactivity data.
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
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Protein Biology
Subcellular Location
Apical cell membrane (Multi-pass membrane protein); Basolateral cell membrane (Multi-pass membrane protein); Cell projection, microvillus membrane (Multi-pass membrane protein); Cell projection, cilium membrane (Multi-pass membrane protein)
Tissue Specificity
Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines
Subunit
Binds cholesterol
Gene: PROM2 | Organism: Homo sapiens | Synonyms: Prominin-like protein 2
Key Publications
- Fargeas C.A. et al. Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins. — J. Biol. Chem. (2003)
- Clark H.F. et al. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. — Genome Res. (2003)
- Ota T. et al. Complete sequencing and characterization of 21,243 full-length human cDNAs. — Nat. Genet. (2004)
- Hillier L.W. et al. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. — Nature (2005)
- Mural R.J. et al. PubMed: CI-5GBDQ6B103N1E (JUL-)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). — Genome Res. (2004)
- Zhang Q. et al. Identification and characterization of a novel testosterone-regulated prominin-like gene in the rat ventral prostate. — Endocrinology (2002)
- Mori T. et al. An ultrastructural and immunohistochemical study of a combined submucosal granular cell tumor and lipoma of the colon showing a unique nodule-in-nodule structure: putative implication of CD34 or prominin-2-positive stromal cells in its histopathogenesis. — Virchows Arch. (2006)
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How do I order or inquire about this product?
Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.
What is the shipping and delivery time?
Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.
How should this product be stored?
Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.
What quality controls are performed on your products?
Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.