Recombinant Human Protein mono-ADP-ribosyltransferase PARP4 (PARP4), partial, Homo sapiens (Human), E.coli, N-terminal 10xHis-tagged, 55.0kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Protein mono-ADP-ribosyltransferase PARP4 (PARP4), partial

Recombinant Human Protein mono-ADP-ribosyltransferase PARP4 (PARP4), partial — Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Purity >90%.

SKU: BCRECP-001338 Categories: ,
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Product Specifications

Product SkuBCRECP-001338
Product DescriptionRecombinant Human Protein mono-ADP-ribosyltransferase PARP4 (PARP4) Protein is expressed from E.coli with N-terminal 10xHis-tagged. It contains 607-1046aa. [Accession | Q9UKK3].
Uniprot No.Q9UKK3
Gene NamesPARP4
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region607-1046aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight55.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Component of the vault particle, which is a massive ribonucleoprotein complex that may play a role in cargo transport and signal transduction.

Biological Context

Subcellular Location: Cytoplasm; Nucleus; Cytoplasm, cytoskeleton, spindle
Tissue Specificity: Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas

Product Specifications

Recombinant Human Protein mono-ADP-ribosyltransferase PARP4 (PARP4), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 607-1046aa, with N-terminal 10xHis-tagged tag, molecular weight 55.0kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins (PubMed:25043379). Component of the vault particle, which is a massive ribonucleoprotein complex that may play a role in cargo transport and signal transduction (PubMed:40691181)

Subcellular Location

Cytoplasm; Nucleus; Cytoplasm, cytoskeleton, spindle

Tissue Specificity

Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas

Subunit

Associates with MVP to form part of the vault particle (PubMed:40691181). The vault is a massive cage-like structure; it consists of a dimer of half-vaults, with each half-vault comprising 39 identical MVP subunits (PubMed:40691181). The two half-vaults assemble to form the complete vault, where minor vault components such as PARP4, TEP1 and vault RNAs (vRNAs) may bind to the interior (PubMed:40691181, PubMed:10477748). Interacts with MVP (via MVP repeats 3 and 4); each MVP subunit binds a single PARP4 molecule, allowing each vault to house up to 78 PARP4 molecules (PubMed:40691181). Interacts with TEP1 (PubMed:10551828, PubMed:15169895)

Gene: PARP4  |  Organism: Homo sapiens  |  Synonyms: 193 kDa vault protein; ADP-ribosyltransferase diphtheria toxin-like 4; PARP-related/IalphaI-related H5/proline-rich; Poly [ADP-ribose] polymerase 4; Vault poly(ADP-ribose) polymerase
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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