Recombinant Human Proto-oncogene tyrosine-protein kinase receptor Ret (RET), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 69.2 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human Proto-oncogene tyrosine-protein kinase receptor Ret (RET), partial (Active)

Recombinant Human Proto-oncogene tyrosine-protein kinase receptor Ret (RET), partial (Active) — recombinant protein, expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000537 Categories: , ,
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Product SKUBCACP-000537
Product DescriptionRecombinant Human Proto-oncogene tyrosine-protein kinase receptor Ret (RET) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 29-635aa. [Accession | P07949].
Uniprot No.P07949
Gene NamesRET
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region29-635aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight69.2 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Macaca mulatta IFNG at 2 μg/mL can bind anti-IFNG recombinant antibody .The EC50 is 35.23-38.98 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesProto-oncogene tyrosine-protein kinase receptor Ret; EC:2.7.10.1; Cadherin family member 12; Proto-oncogene c-Ret; Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment; RET; CDHF12, CDHR16, PTC

Function

Isoform 1 in complex with GFRAL induces higher activation of MAPK-signaling pathway than isoform 2 in complex with GFRAL.

Product Specifications

Recombinant Human Proto-oncogene tyrosine-protein kinase receptor Ret (RET), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 29-635aa, with C-terminal 10xHis-tagged tag, molecular weight 69.2 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Macaca mulatta IFNG at 2 μg/mL can bind anti-IFNG recombinant antibody .The EC50 is 35.23-38.98 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Isoform 1 in complex with GFRAL induces higher activation of MAPK-signaling pathway than isoform 2 in complex with GFRAL

Gene: RET  |  Organism: Homo sapiens

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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