Recombinant Human Pulmonary surfactant-associated protein C (SFTPC)

Recombinant Human Pulmonary surfactant-associated protein C (SFTPC) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-001625 Category:

Product Specifications

Product SkuBCRECP-001625
Product DescriptionRecombinant Human Pulmonary surfactant-associated protein C (SFTPC) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 24-58aa. [Accession | P11686].
Uniprot No.P11686
Gene NamesSFTPC
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region24-58aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight30.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.

Biological Context

Subcellular Location: Secreted, extracellular space, surface film
Disease Association: Pulmonary surfactant metabolism dysfunction 2 (SMDP2) : A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Pulmonary surfactant-associated protein C (SFTPC) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 24-58aa, with N-terminal GST-tagged tag, molecular weight 30.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces

Subcellular Location

Secreted, extracellular space, surface film

Disease Association

Pulmonary surfactant metabolism dysfunction 2 (SMDP2) : A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. [The disease is caused by variants affecting the gene represented in this entry]

Gene: SFTPC  |  Organism: Homo sapiens  |  Synonyms: Pulmonary surfactant-associated protein C; Pulmonary surfactant-associated proteolipid SPL(Val); SP5
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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