Recombinant Human Rho-related GTP-binding protein RhoD (RHOD) — Involved in endosome dynamics. Purity >90%.
| Product Sku | BCRECP-001535 |
| Product Description | Recombinant Human Rho-related GTP-binding protein RhoD (RHOD) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1-207aa. [Accession | O00212]. |
| Uniprot No. | O00212 |
| Gene Names | RHOD |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Expression System | E.coli |
| Expression Region | 1-207aa |
| Species | Homo sapiens (Human) |
| Tag Info | N-terminal 10xHis-tagged and C-terminal Myc-tagged |
| Molecular weight | 30.6kDa |
| Activity | Please contact us to obtain bioactivity data. |
| Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose. |
| Storage | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| Research Areas | Signal Transduction |
Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton.
Recombinant Human Rho-related GTP-binding protein RhoD (RHOD) — Involved in endosome dynamics. Purity >90%. Suitable for ELISA and Western Blot applications.
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Please contact us to obtain bioactivity data.
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution
Cell membrane (Lipid-anchor); Early endosome
Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues
Interacts (in GTP-bound form) with DIAPH2 isoform 3 (PubMed:12577064). Interacts (in GTP-bound form) with DAPK3 (PubMed:23454120). Interacts (in GTP-bound form) with FILIP1 (PubMed:12577064). Interacts (in GTP-bound form) with WHAMM (By similarity). Interacts with PAK5 (PubMed:17064668). Interacts (independent of GTP-loaded status) with ANKFY1 (PubMed:24102721). Interacts with PLXNB2 (PubMed:34114565)
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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.
Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.
Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.
