Recombinant Human Serpin H1 (SERPINH1), Homo sapiens (Human), E.coli, N-terminal 10xHis-tagged, 50.6kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Serpin H1 (SERPINH1)

Recombinant Human Serpin H1 (SERPINH1) — Binds specifically to collagen. Purity >90%.

SKU: BCRECP-001619 Category:
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Product Specifications

Product SkuBCRECP-001619
Product DescriptionRecombinant Human Serpin H1 (SERPINH1) Protein is expressed from E.coli with N-terminal 10xHis-tagged. It contains 19-418aa. [Accession | P50454].
Uniprot No.P50454
Gene NamesSERPINH1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region19-418aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight50.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

Biological Context

Subcellular Location: Endoplasmic reticulum lumen
Disease Association: Osteogenesis imperfecta 10 (OI10) : A form of osteogenesis imperfecta, a disorder of bone formation characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI10 is an autosomal recessive form characterized by multiple bone deformities and fractures, generalized osteopenia, dentinogenesis imperfecta, and blue sclerae. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Serpin H1 (SERPINH1) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 19-418aa, with N-terminal 10xHis-tagged tag, molecular weight 50.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen

Subcellular Location

Endoplasmic reticulum lumen

Disease Association

Osteogenesis imperfecta 10 (OI10) : A form of osteogenesis imperfecta, a disorder of bone formation characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI10 is an autosomal recessive form characterized by multiple bone deformities and fractures, generalized osteopenia, dentinogenesis imperfecta, and blue sclerae. [The disease is caused by variants affecting the gene represented in this entry]

Gene: SERPINH1  |  Organism: Homo sapiens  |  Synonyms: 47 kDa heat shock protein; Arsenic-transactivated protein 3; Cell proliferation-inducing gene 14 protein; Collagen-binding protein; Rheumatoid arthritis-related antigen RA-A47
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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