Recombinant Human Sodium/iodide cotransporter (SLC5A5), partial, Homo sapiens (Human), E.coli, C-terminal 6xHis-tagged, 17.4kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Sodium/iodide cotransporter (SLC5A5), partial

Recombinant Human Sodium/iodide cotransporter (SLC5A5), partial — Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland. Purity >90%.

SKU: BCRECP-001657 Category:
Online Inquiry →

Product Specifications

Product SkuBCRECP-001657
Product DescriptionRecombinant Human Sodium/iodide cotransporter (SLC5A5) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 547-643aa. [Accession | Q92911].
Uniprot No.Q92911
Gene NamesSLC5A5
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region547-643aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight17.4kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland. Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein); Cytoplasm
Tissue Specificity: Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors
Disease Association: Thyroid dyshormonogenesis 1 (TDH1) : A disorder characterized by the inability of the thyroid to maintain a concentration difference of readily exchangeable iodine between the plasma and the thyroid gland, leading to congenital hypothyroidism. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Sodium/iodide cotransporter (SLC5A5), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 547-643aa, with C-terminal 6xHis-tagged tag, molecular weight 17.4kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland (PubMed:12488351, PubMed:18372236, PubMed:18708479, PubMed:20797386, PubMed:31310151, PubMed:32084174, PubMed:8806637, PubMed:9329364). Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate (PubMed:12488351)

Subcellular Location

Cell membrane (Multi-pass membrane protein); Cytoplasm

Disease Association

Thyroid dyshormonogenesis 1 (TDH1) : A disorder characterized by the inability of the thyroid to maintain a concentration difference of readily exchangeable iodine between the plasma and the thyroid gland, leading to congenital hypothyroidism. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors

Subunit

Monomer

Gene: SLC5A5  |  Organism: Homo sapiens  |  Synonyms: Natrium iodide transporter; Sodium-iodide symporter; Solute carrier family 5 member 5
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top