Recombinant Human Somatotropin (GH1), Biotinylated, Homo sapiens (Human), Mammalian cell, N-terminal 10xHis-tagged and C-terminal Avi-tagged, 26.7kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Somatotropin (GH1), Biotinylated

Recombinant Human Somatotropin (GH1), Biotinylated — Plays an important role in growth control. Purity >90%.

SKU: BCRECP-000740 Categories: , ,
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Product Specifications

Product SkuBCRECP-000740
Product DescriptionRecombinant Human Somatotropin (GH1) Protein is expressed from Mammalian cell with N-terminal 10xHis-tagged and C-terminal Avi-tagged. It contains 27-217aa. [Accession | P01241].
Uniprot No.P01241
Gene NamesGH1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region27-217aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged and C-terminal Avi-tagged
Molecular weight26.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasDevelopmental Biology

Function

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF1. It stimulates both the differentiation and proliferation of myoblasts.

Biological Context

Subcellular Location: Secreted
Disease Association: Growth hormone deficiency, isolated, 1A (IGHD1A) : An autosomal recessive, severe deficiency of growth hormone leading to dwarfism. Patients often develop antibodies to administered growth hormone. [The disease is caused by variants affecting the gene represented in this entry] | Growth hormone deficiency, isolated, 1B (IGHD1B) : An autosomal recessive deficiency of growth hormone leading to short stature. Patients have low but detectable levels of growth hormone, significantly retarded bone age, and a positive response and immunologic tolerance to growth hormone therapy. [The disease is caused by variants affecting the gene represented in this entry] | Kowarski syndrome (KWKS) : A syndrome clinically characterized by short stature associated with bioinactive growth hormone, normal or slightly increased growth hormone secretion, pathologically low insulin-like growth factor 1 levels, and normal catch-up growth on growth hormone replacement therapy. [The disease is caused by variants affecting the gene represented in this entry] | Growth hormone deficiency, isolated, 2 (IGHD2) : An autosomal dominant deficiency of growth hormone leading to short stature. Clinical severity is variable. Patients have a positive response and immunologic tolerance to growth hormone therapy. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Somatotropin (GH1), Biotinylated is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 27-217aa, with N-terminal 10xHis-tagged and C-terminal Avi-tagged tag, molecular weight 26.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues

Subcellular Location

Secreted

Disease Association

Growth hormone deficiency, isolated, 1A (IGHD1A) : An autosomal recessive, severe deficiency of growth hormone leading to dwarfism. Patients often develop antibodies to administered growth hormone. [The disease is caused by variants affecting the gene represented in this entry] | Growth hormone deficiency, isolated, 1B (IGHD1B) : An autosomal recessive deficiency of growth hormone leading to short stature. Patients have low but detectable levels of growth hormone, significantly retarded bone age, and a positive response and immunologic tolerance to growth hormone therapy. [The disease is caused by variants affecting the gene represented in this entry] | Kowarski syndrome (KWKS) : A syndrome clinically characterized by short stature associated with bioinactive growth hormone, normal or slightly increased growth hormone secretion, pathologically low insulin-like growth factor 1 levels, and normal catch-up growth on growth hormone replacement therapy. [The disease is caused by variants affecting the gene represented in this entry] | Growth hormone deficiency, isolated, 2 (IGHD2) : An autosomal dominant deficiency of growth hormone leading to short stature. Clinical severity is variable. Patients have a positive response and immunologic tolerance to growth hormone therapy. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

Monomer, dimer, trimer, tetramer and pentamer, disulfide-linked or non-covalently associated, in homomeric and heteromeric combinations. Can also form a complex either with GHBP or with the alpha2-macroglobulin complex

Gene: GH1  |  Organism: Homo sapiens  |  Synonyms: Growth hormone; Growth hormone 1; Pituitary growth hormone
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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