Recombinant Human T-cell antigen CD7 (CD7), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal hFc1-Myc-tagged, 46.5 kDa, purity >90% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
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Recombinant Human T-cell antigen CD7 (CD7), partial (Active)

Recombinant Human T-cell antigen CD7 (CD7), partial (Active) — Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Purity >90%.

SKU: BCACP-000092 Categories: ,
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Product SKUBCACP-000092
Product DescriptionRecombinant Human T-cell antigen CD7 (CD7) protein is expressed from Mammalian cell with C-terminal hFc1-Myc-tagged. It contains 26-180aa. [Accession | P09564].
Uniprot No.P09564
Gene NamesCD7
PurityGreater than 90% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region26-180aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-Myc-tagged
Molecular weight46.5 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized SARS-CoV S-RBD at 2 μg/ml can bind Paguma larvata ACE2, the EC50 is 5.056-7.559 ng/ml.;Recombinant Paguma larvata ACE2 protein enzyme activity is measured by its ability to cleave fluorogenic peptide substrate(Mca-Ala-Pro-Lys(Dnp)-OH), The Km is 22.84 μM.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative Names(GP40)(T-cell leukemia antigen)(T-cell surface antigen Leu-9)(TP41)

Function

Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)
Tissue Specificity: Expressed on T-cells and natural killer (NK) cells and their precursors

Product Specifications

Recombinant Human T-cell antigen CD7 (CD7), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 26-180aa, with C-terminal hFc1-Myc-tagged tag, molecular weight 46.5 kDa, purity Greater than 90% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors (PubMed:7506726). Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1 (PubMed:10652336). In turn, mediates the production of cytokines such as IL-2 (PubMed:1709867). On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels (PubMed:7506726)

Subcellular Location

Membrane (Single-pass type I membrane protein)

Tissue Specificity

Expressed on T-cells and natural killer (NK) cells and their precursors

Subunit

Interacts with SECTM1

Gene: CD7  |  Organism: Homo sapiens  |  Synonyms: GP40; T-cell leukemia antigen; T-cell surface antigen Leu-9; TP41
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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