Recombinant Human Talin-1 (TLN1), partial

Recombinant Human Talin-1 (TLN1), partial — High molecular weight cytoskeletal protein concentrated at regions of cell-matrix and cell-cell contacts. Purity >90%.

SKU: BCRECP-001778 Category:

Product Specifications

Product SkuBCRECP-001778
Product DescriptionRecombinant Human Talin-1 (TLN1) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 92-399aa. [Accession | Q9Y490].
Uniprot No.Q9Y490
Gene NamesTLN1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region92-399aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight62.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

High molecular weight cytoskeletal protein concentrated at regions of cell-matrix and cell-cell contacts. Involved in connections of major cytoskeletal structures to the plasma membrane. With KANK1 co-organize the assembly of cortical microtubule stabilizing complexes (CMSCs) positioned to control microtubule-actin crosstalk at focal adhesions (FAs) rims.

Biological Context

Subcellular Location: Cell projection, ruffle membrane (Peripheral membrane protein); Cytoplasm, cytoskeleton; Cell surface; Cell junction, focal adhesion
Tissue Specificity: Expressed at low to non-detectable levels in many tissues but highly expressed in skin and pancreas with other tissues including kidney cortex, endocervix, testis, pituitary, liver, and spleen also showing robust expression

Product Specifications

Recombinant Human Talin-1 (TLN1), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 92-399aa, with N-terminal GST-tagged tag, molecular weight 62.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

High molecular weight cytoskeletal protein concentrated at regions of cell-matrix and cell-cell contacts. Involved in connections of major cytoskeletal structures to the plasma membrane. With KANK1 co-organize the assembly of cortical microtubule stabilizing complexes (CMSCs) positioned to control microtubule-actin crosstalk at focal adhesions (FAs) rims

Subcellular Location

Cell projection, ruffle membrane (Peripheral membrane protein); Cytoplasm, cytoskeleton; Cell surface; Cell junction, focal adhesion

Tissue Specificity

Expressed at low to non-detectable levels in many tissues but highly expressed in skin and pancreas with other tissues including kidney cortex, endocervix, testis, pituitary, liver, and spleen also showing robust expression

Subunit

(Microbial infection) Interacts with human cytomegalovirus protein UL135

Gene: TLN1  |  Organism: Homo sapiens
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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