Recombinant Human Thioredoxin (TXN) (Active)

Recombinant Human Thioredoxin (TXN) (Active) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >95%.

SKU: BCACP-001088 Category:
Product SKUBCACP-001088
Product DescriptionRecombinant Human Thioredoxin (TXN) protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 1-105aa. [Accession | P10599].
Uniprot No.P10599
Gene NamesTXN
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-105aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight13.9 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Anti-Human Nectin-4 mAb-mFc at 2μg/ml can bind Human Nectin-4-His, the ED50 of Human Nectin-4-His is 16.29 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesADF; ATL derived factor; ATL-derived factor; DKFZp686B1993; MGC61975; SASP; Surface associated sulphydryl protein; Surface-associated sulphydryl protein; testicular tissue protein Li 199; THIO_HUMAN; Thioredoxin; thioredoxin delta 3; TRDX; TRX 1; Trx; TRX1; TXN; TXN delta 3; TXN protein; zgc:92903

Function

ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).

Product Specifications

Recombinant Human Thioredoxin (TXN) (Active) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >95%. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Anti-Human Nectin-4 mAb-mFc at 2μg/ml can bind Human Nectin-4-His, the ED50 of Human Nectin-4-His is 16.29 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55)

Subcellular Location

Nucleus; Cytoplasm; Secreted

Subunit

Homodimer; disulfide-linked (PubMed:17260951, PubMed:9369469). Interacts with TXNIP through the redox-active site (PubMed:17260951). Interacts with MAP3K5 and CASP3 (PubMed:15246877). In case of infection, interacts with S.typhimurium protein slrP (PubMed:19690162). Interacts with APEX1; the interaction stimulates the FOS/JUN AP-1 DNA-binding activity in a redox-dependent manner (PubMed:9108029)

Gene: TXN  |  Organism: Homo sapiens  |  Synonyms: ATL-derived factor; Surface-associated sulphydryl protein
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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