Recombinant Human Transcriptional coactivator YAP1 (YAP1), Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 83.4kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Transcriptional coactivator YAP1 (YAP1)

Recombinant Human Transcriptional coactivator YAP1 (YAP1) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCRECP-001920 Category:
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Product Specifications

Product SkuBCRECP-001920
Product DescriptionRecombinant Human Transcriptional coactivator YAP1 (YAP1) Protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 1-504aa. [Accession | P46937].
Uniprot No.P46937
Gene NamesYAP1
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region1-504aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight83.4kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Activates the C-terminal fragment (CTF) of ERBB4 (isoform 3).

Biological Context

Subcellular Location: Cytoplasm; Nucleus; Cell junction, tight junction; Cell membrane
Tissue Specificity: Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level)
Disease Association: Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or impaired intellectual development (COB1) : An autosomal dominant disease characterized by uveal colobomata, microphthalmia, cataract and cleft lip/palate. Considerable variability is observed among patients, uveal colobomata being the most constant feature. Some patients manifest intellectual disability of varying degree and/or sensorineural, mid-frequency hearing loss. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Transcriptional coactivator YAP1 (YAP1) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 1-504aa, with C-terminal hFc1-tagged tag, molecular weight 83.4kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Activates the C-terminal fragment (CTF) of ERBB4 (isoform 3)

Subcellular Location

Cytoplasm; Nucleus; Cell junction, tight junction; Cell membrane

Disease Association

Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or impaired intellectual development (COB1) : An autosomal dominant disease characterized by uveal colobomata, microphthalmia, cataract and cleft lip/palate. Considerable variability is observed among patients, uveal colobomata being the most constant feature. Some patients manifest intellectual disability of varying degree and/or sensorineural, mid-frequency hearing loss. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level)

Subunit

Interacts (via WW domain 1) with isoform 3 of ERBB4 (via PPxY motif 2)

Gene: YAP1  |  Organism: Homo sapiens  |  Synonyms: Protein yorkie homolog; Yes-associated protein YAP65 homolog
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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