Recombinant Human Translocator protein (TSPO) Protein, Homo sapiens (Human), in vitro E.coli expression system, N-terminal 10xHis-tagged, 20.2kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Translocator protein (TSPO) Protein

Recombinant Human Translocator protein (TSPO) Protein — Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Purity >85%.

SKU: BCRECP-00071TM Category:
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Product Specifications

Uniprot No.P30536
Gene NamesTSPO
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region2-169aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight20.2kDa
ActivityNot Test
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism , but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis.

Biological Context

Subcellular Location: Mitochondrion membrane (Multi-pass membrane protein)
Tissue Specificity: Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids

Product Specifications

Recombinant Human Translocator protein (TSPO) Protein is a recombinant protein from Homo sapiens (Human), expressed in in vitro E.coli expression system, covering amino acids 2-169aa, with N-terminal 10xHis-tagged tag, molecular weight 20.2kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not Test

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678)

Subcellular Location

Mitochondrion membrane (Multi-pass membrane protein)

Tissue Specificity

Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids

Subunit

Interacts with TSPOAP1 (By similarity). May interact with STAR (By similarity). Interacts with MOST-1. Interacts with TMEM97 (PubMed:37047353). Forms a complex with TMEM97 and PGRMC1; the interaction occurs in MIA PaCa-2 cells but not in MCF7 cells (PubMed:37047353)

Gene: TSPO  |  Organism: Homo sapiens  |  Synonyms: Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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