Recombinant Human Tumor necrosis factor ligand superfamily member 1 (TNFSF15), partial, Homo sapiens (Human), Mammalian cell, N-terminal 10xHis-tagged, 20.0kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Tumor necrosis factor ligand superfamily member 1 (TNFSF15), partial

Recombinant Human Tumor necrosis factor ligand superfamily member 1 (TNFSF15), partial — Cytokine that signals through TNFRSF25 receptor. Purity >90%.

SKU: BCRECP-001809 Categories: ,
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Product Specifications

Product SkuBCRECP-001809
Product DescriptionRecombinant Human Tumor necrosis factor ligand superfamily member 1 (TNFSF15) Protein is expressed from Mammalian cell with N-terminal 10xHis-tagged. It contains 23-174aa. [Accession | O95150].
Uniprot No.O95150
Gene NamesTNFSF15
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region23-174aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight20.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

Cytokine that signals through TNFRSF25 receptor. Functions as a T-cell costimulator, that increases IL-2 responsiveness and secretion of proinflammatory cytokines which enhances T-cell activation, proliferation and the survival of activated T-cells. Inhibits vascular endothelial growth and angiogenesis (in vitro).

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon

Product Specifications

Recombinant Human Tumor necrosis factor ligand superfamily member 1 (TNFSF15), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 23-174aa, with N-terminal 10xHis-tagged tag, molecular weight 20.0kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Cytokine that signals through TNFRSF25 receptor (PubMed:11911831). Functions as a T-cell costimulator, that increases IL-2 responsiveness and secretion of proinflammatory cytokines which enhances T-cell activation, proliferation and the survival of activated T-cells (PubMed:10597252, PubMed:11911831). Inhibits vascular endothelial growth and angiogenesis (in vitro) (PubMed:11923219, PubMed:9872942). Binds to the decoy receptor TNFRSF6B, blocking the activation normally triggered by TNFSF15 and leading to decreased T-cell activation and reduced inflammation (PubMed:21300286)

Subcellular Location

Secreted

Tissue Specificity

Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon

Subunit

Homotrimer (PubMed:17935696). TNFSF15 binds TNFRSF6B with 3:3 stoichiometry (PubMed:21300286)

Gene: TNFSF15  |  Organism: Homo sapiens  |  Synonyms: TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitor
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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