Recombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15),partial,Biotinylated (Active), Homo sapiens (Human), Mammalian cell, N-terminal 10xHis-Avi-tagged, 25.4 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15),partial,Biotinylated (Active)

Recombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15),partial,Biotinylated (Active) — Cytokine that signals through TNFRSF25 receptor. Purity >95%.

SKU: BCACP-000281 Categories: , , ,
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Product SKUBCACP-000281
Product DescriptionRecombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15), Biotinylated protein is expressed from Mammalian cell with N-terminal 10xHis-Avi-tagged. It contains 72-251aa. [Accession | O95150].
Uniprot No.O95150
Gene NamesTNFSF15
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region72-251aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-Avi-tagged
Molecular weight25.4 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis CDH6 at 2 μg/mL can bind Anti-CDH6 recombinant antibody . The EC50 is 2.076-2.371 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesTL1, VEGI

Function

Cytokine that signals through TNFRSF25 receptor. Functions as a T-cell costimulator, that increases IL-2 responsiveness and secretion of proinflammatory cytokines which enhances T-cell activation, proliferation and the survival of activated T-cells. Inhibits vascular endothelial growth and angiogenesis (in vitro).

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon

Product Specifications

Recombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15),partial,Biotinylated (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 72-251aa, with N-terminal 10xHis-Avi-tagged tag, molecular weight 25.4 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis CDH6 at 2 μg/mL can bind Anti-CDH6 recombinant antibody . The EC50 is 2.076-2.371 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Cytokine that signals through TNFRSF25 receptor (PubMed:11911831). Functions as a T-cell costimulator, that increases IL-2 responsiveness and secretion of proinflammatory cytokines which enhances T-cell activation, proliferation and the survival of activated T-cells (PubMed:10597252, PubMed:11911831). Inhibits vascular endothelial growth and angiogenesis (in vitro) (PubMed:11923219, PubMed:9872942). Binds to the decoy receptor TNFRSF6B, blocking the activation normally triggered by TNFSF15 and leading to decreased T-cell activation and reduced inflammation (PubMed:21300286)

Subcellular Location

Secreted

Tissue Specificity

Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon

Subunit

Homotrimer (PubMed:17935696). TNFSF15 binds TNFRSF6B with 3:3 stoichiometry (PubMed:21300286)

Gene: TNFSF15  |  Organism: Homo sapiens  |  Synonyms: TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitor
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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