Recombinant Human Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b Protein, HEK293 Cells, C-6His, 19.0 kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b Protein

Recombinant Human Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b Protein — Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. Purity >90%.

SKU: BCRETP-000048 Categories: , ,
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Product Specifications

Product SkuBCRETP-000048
Product DescriptionRecombinant Human Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b Protein is expressed from HEK293 with His tag at the C-Terminus. It contains 288-461aa. [Accession | P20333].
Uniprot No.P20333
SynonymsTumor necrosis factor receptor superfamily member 1B;Tumor necrosis factor receptor 2;TNF-R2;Tumor necrosis factor receptor type II;TNF-RII;TNFR-II;p75;p80 TNF-alpha receptor
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemHEK293 Cells
Expression Region288-461aa
Tag InfoC-6His
Molecular weight19.0 kDa
EndotoxinLess than 1.0 EU/μg as determined by LAL method.

Function

Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF.

Product Specifications

Recombinant Human Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b Protein is a recombinant protein, expressed in HEK293 Cells, covering amino acids 288-461aa, with C-6His tag, molecular weight 19.0 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitol

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity

Gene: TNFRSF1B  |  Organism: Homo sapiens

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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