Function
Receptor for angiotensin II, a vasoconstricting peptide. Primarily signals via a non-canonical G protein- and beta-arrestin independent pathways. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
Biological Context
Subcellular Location: Cell membrane (Multi-pass membrane protein)
Tissue Specificity: In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine
Product Specifications
Recombinant Human Type-2 angiotensin II receptor (AGTR2) Protein is a recombinant protein from Homo sapiens (Human), expressed in in vitro E.coli expression system, covering amino acids 1-363aa, with N-terminal 6xHis-tagged tag, molecular weight 42.1kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
