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Recombinant Human Tyrosine-protein kinase transmembrane receptor ROR2 (ROR2), partial (Active)

Recombinant Human Tyrosine-protein kinase transmembrane receptor ROR2 (ROR2), partial (Active) — Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. Purity >95%.

SKU: BCACP-000518 Categories: , ,
Product SKUBCACP-000518
Product DescriptionRecombinant Human Tyrosine-protein kinase transmembrane receptor ROR2 (ROR2) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 34-403aa. [Accession | Q01974].
Uniprot No.Q01974
Gene NamesROR2
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region34-403aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight42.7 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Mouse Kitlg at 2 μg/mL can bind Mouse Kit.The EC50 is 15.57-20.95 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesTyrosine-protein kinase transmembrane receptor ROR2; EC 2.7.10.1; Neurotrophic tyrosine kinase, receptor-related 2

Function

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation.

Product Specifications

Recombinant Human Tyrosine-protein kinase transmembrane receptor ROR2 (ROR2), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 34-403aa, with C-terminal 10xHis-tagged tag, molecular weight 42.7 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443)

Gene: ROR2  |  Organism: Homo sapiens

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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