Recombinant Human Urocortin-3 (UCN3), Homo sapiens (Human), E.coli, N-terminal 6xHis-KSI-tagged, 20.1kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Urocortin-3 (UCN3)

Recombinant Human Urocortin-3 (UCN3) — Hormone that plays a central role in whole body adaptation to stress. Purity >90%.

SKU: BCRECP-001890 Category:
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Product Specifications

Product SkuBCRECP-001890
Product DescriptionRecombinant Human Urocortin-3 (UCN3) Protein is expressed from E.coli with N-terminal 6xHis-KSI-tagged. It contains 119-161aa. [Accession | Q969E3].
Uniprot No.Q969E3
Gene NamesUCN3
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region119-161aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-KSI-tagged
Molecular weight20.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Hormone that plays a central role in whole body adaptation to stress. Released by the hypothalamus primarily in response to physical or psychological stress and acts by binding to CRH receptor CRHR2. UCN3-dependent signaling plays a key role in the metabolic regulation and energy homeostasis in responses to stress, acting as an anxiolytic.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Human Urocortin-3 (UCN3) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 119-161aa, with N-terminal 6xHis-KSI-tagged tag, molecular weight 20.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Hormone that plays a central role in whole body adaptation to stress (PubMed:11329063, PubMed:11416224). Released by the hypothalamus primarily in response to physical or psychological stress and acts by binding to CRH receptor CRHR2 (PubMed:11329063, PubMed:11416224, PubMed:20966082, PubMed:26350463). UCN3-dependent signaling plays a key role in the metabolic regulation and energy homeostasis in responses to stress, acting as an anxiolytic (PubMed:11329063, PubMed:11416224). Promotes energy balance by reducing food intake, improving insulin sensitivity and managing blood glucose levels in response to metabolic stress (By similarity). In contrast to CRH and UCN, does not activate the hypothalamus-pituitary-adrenal axis to promote corticotropin hormone (ACTH) production (PubMed:11329063)

Subcellular Location

Secreted

Gene: UCN3  |  Organism: Homo sapiens  |  Synonyms: Stresscopin; Urocortin III
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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