Recombinant Human Urocortin-3 (UCN3), Homo sapiens (Human), E.coli, N-terminal 6xHis-KSI-tagged, 20.1kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Urocortin-3 (UCN3)

Recombinant Human Urocortin-3 (UCN3) — Hormone that plays a central role in whole body adaptation to stress. Purity >90%.

SKU: BCRECP-001890 Category:
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Product Specifications

Product SkuBCRECP-001890
Product DescriptionRecombinant Human Urocortin-3 (UCN3) Protein is expressed from E.coli with N-terminal 6xHis-KSI-tagged. It contains 119-161aa. [Accession | Q969E3].
Uniprot No.Q969E3
Gene NamesUCN3
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region119-161aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-KSI-tagged
Molecular weight20.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Hormone that plays a central role in whole body adaptation to stress. Released by the hypothalamus primarily in response to physical or psychological stress and acts by binding to CRH receptor CRHR2. UCN3-dependent signaling plays a key role in the metabolic regulation and energy homeostasis in responses to stress, acting as an anxiolytic.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Human Urocortin-3 (UCN3) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 119-161aa, with N-terminal 6xHis-KSI-tagged tag, molecular weight 20.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Hormone that plays a central role in whole body adaptation to stress (PubMed:11329063, PubMed:11416224). Released by the hypothalamus primarily in response to physical or psychological stress and acts by binding to CRH receptor CRHR2 (PubMed:11329063, PubMed:11416224, PubMed:20966082, PubMed:26350463). UCN3-dependent signaling plays a key role in the metabolic regulation and energy homeostasis in responses to stress, acting as an anxiolytic (PubMed:11329063, PubMed:11416224). Promotes energy balance by reducing food intake, improving insulin sensitivity and managing blood glucose levels in response to metabolic stress (By similarity). In contrast to CRH and UCN, does not activate the hypothalamus-pituitary-adrenal axis to promote corticotropin hormone (ACTH) production (PubMed:11329063)

Subcellular Location

Secreted

Gene: UCN3  |  Organism: Homo sapiens  |  Synonyms: Stresscopin; Urocortin III
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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