Recombinant Human YTH domain-containing family protein 2 (YTHDF2), Homo sapiens (Human), E.coli, N-terminal 10xHis-tagged, 68.2kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human YTH domain-containing family protein 2 (YTHDF2)

Recombinant Human YTH domain-containing family protein 2 (YTHDF2) — (Microbial infection) Promotes viral gene expression and virion production of kaposis sarcoma-associated herpesvirus (KSHV) at some stage of the KSHV life cycle (in iSLK. Purity >85%.

SKU: BCRECP-001927 Category:
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Product Specifications

Product SkuBCRECP-001927
Product DescriptionRecombinant Human YTH domain-containing family protein 2 (YTHDF2) Protein is expressed from E.coli with N-terminal 10xHis-tagged. It contains 2-579aa. [Accession | Q9Y5A9].
Uniprot No.Q9Y5A9
Gene NamesYTHDF2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region2-579aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight68.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Biology

Function

(Microbial infection) Promotes viral gene expression and virion production of kaposis sarcoma-associated herpesvirus (KSHV) at some stage of the KSHV life cycle (in iSLK.219 and iSLK.BAC16 cells). Acts by binding to N6-methyladenosine (m6A)-containing viral RNAs.

Biological Context

Subcellular Location: Cytoplasm, cytosol; Cytoplasm, P-body; Cytoplasm, Stress granule; Nucleus
Tissue Specificity: Highly expressed in induced pluripotent stem cells (iPSCs) and down-regulated during neural differentiation

Product Specifications

Recombinant Human YTH domain-containing family protein 2 (YTHDF2) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 2-579aa, with N-terminal 10xHis-tagged tag, molecular weight 68.2kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Promotes viral gene expression and virion production of kaposis sarcoma-associated herpesvirus (KSHV) at some stage of the KSHV life cycle (in iSLK.219 and iSLK.BAC16 cells) (PubMed:29659627). Acts by binding to N6-methyladenosine (m6A)-containing viral RNAs (PubMed:29659627)

Subcellular Location

Cytoplasm, cytosol; Cytoplasm, P-body; Cytoplasm, Stress granule; Nucleus

Tissue Specificity

Highly expressed in induced pluripotent stem cells (iPSCs) and down-regulated during neural differentiation

Subunit

Interacts with CNOT1; interaction is direct and promotes recruitment of the CCR4-NOT complex (PubMed:27558897, PubMed:32492408). Interacts with YTHDF3 (PubMed:28106072). Interacts with RIDA/HRSP12; interaction leads to recruitment of the ribonuclease P/MRP complex (PubMed:30930054)

Gene: YTHDF2  |  Organism: Homo sapiens  |  Synonyms: CLL-associated antigen KW-14; High-glucose-regulated protein 8; Renal carcinoma antigen NY-REN-2
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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