Recombinant Influenza A virus Matrix protein 1 (M1), partial, Influenza A virus, E.coli, N-terminal 10xHis-tagged, 19.3kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Influenza A virus Matrix protein 1 (M1), partial

Recombinant Influenza A virus Matrix protein 1 (M1), partial — Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. Purity >90%.

SKU: BCRECP-003335 Categories: , ,
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Product Specifications

Product SkuBCRECP-003335
Product DescriptionRecombinant Influenza A virus Matrix protein 1 (M1) Protein is expressed from E.coli with N-terminal 10xHis-tagged. It contains 133-252aa. [Accession | A0A2I8BGF8].
Uniprot No.A0A2I8BGF8
Gene NamesM1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region133-252aa
SpeciesInfluenza A virus
Tag InfoN-terminal 10xHis-tagged
Molecular weight19.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells.

Product Specifications

Recombinant Influenza A virus Matrix protein 1 (M1), partial is a recombinant protein, expressed in E.coli, covering amino acids 133-252aa, with N-terminal 10xHis-tagged tag, molecular weight 19.3kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place

Gene: M1  |  Organism: Influenza A virus

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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