Recombinant Macaca fascicularis Interleukin-2 receptor subunit alpha (IL2RA), partial (Active), Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), Mammalian cell, C-terminal 10xHis-tagged, 26.1 kDa, purity >95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
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Recombinant Macaca fascicularis Interleukin-2 receptor subunit alpha (IL2RA), partial (Active)

Recombinant Macaca fascicularis Interleukin-2 receptor subunit alpha (IL2RA), partial (Active) — Receptor for interleukin-2. Purity >95%.

SKU: BCACP-000608 Categories: ,
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Product SKUBCACP-000608
Product DescriptionRecombinant Cynomolgus monkey Interleukin-2 receptor subunit alpha (IL2RA) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 22-238aa. [Accession | H6WS54].
Uniprot No.H6WS54
Gene NamesIL2RA
PurityGreater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region22-238aa
SpeciesMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Tag InfoC-terminal 10xHis-tagged
Molecular weight26.1 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Human SIRPB1 at 2 μg/mL can bind anti-SIRPB1 recombinant antibody.The EC50 is 0.9675-1.114 ng/mL.;SIRPB1 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Human SIRPB1 with an affinity constant of 0.245 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesInterleukin-2 receptor subunit alpha

Function

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)

Product Specifications

Recombinant Macaca fascicularis Interleukin-2 receptor subunit alpha (IL2RA), partial (Active) is a recombinant protein from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), expressed in Mammalian cell, covering amino acids 22-238aa, with C-terminal 10xHis-tagged tag, molecular weight 26.1 kDa, purity Greater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Human SIRPB1 at 2 μg/mL can bind anti-SIRPB1 recombinant antibody.The EC50 is 0.9675-1.114 ng/mL.;SIRPB1 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Human SIRPB1 with an affinity constant of 0.245 nM as detected by MetaSPR Assay (WeSPRTM 200).

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells

Subcellular Location

Membrane (Single-pass type I membrane protein)

Subunit

Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit

Organism: Macaca fascicularis

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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