Function
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
Biological Context
Subcellular Location: Cell membrane (Single-pass type I membrane protein)
Product Specifications
Recombinant Macaca fascicularis Trophoblast glycoprotein (TPBG), partial (Active) is a recombinant protein from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), expressed in Mammalian cell, covering amino acids 35-355aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 39.9kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
