Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial, Mus musculus (Mouse), Baculovirus, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 18.2kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial

Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial — recombinant protein from Mus musculus (Mouse), expressed in Baculovirus. Purity >85%.

SKU: BCRECP-003304 Category:
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Product Specifications

Product SkuBCRECP-003304
Product DescriptionRecombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1) Protein is expressed from Baculovirus with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 248-360aa. [Accession | P55302].
Uniprot No.P55302
Gene NamesLrpap1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region248-360aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight18.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasMetabolism

Function

Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.

Biological Context

Subcellular Location: Rough endoplasmic reticulum lumen; Endoplasmic reticulum-Golgi intermediate compartment lumen; Golgi apparatus, cis-Golgi network; Golgi apparatus lumen; Endosome lumen; Cell surface
Tissue Specificity: Highly expressed in PYS-2 parietal endoderm cells and in the kidney. The RNA level increased about 10-fold during differentiation of F9 embryonal carcinoma cells to parietal endoderm cells

Product Specifications

Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial is a recombinant protein from Mus musculus (Mouse), expressed in Baculovirus, covering amino acids 248-360aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 18.2kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway

Subcellular Location

Rough endoplasmic reticulum lumen; Endoplasmic reticulum-Golgi intermediate compartment lumen; Golgi apparatus, cis-Golgi network; Golgi apparatus lumen; Endosome lumen; Cell surface

Tissue Specificity

Highly expressed in PYS-2 parietal endoderm cells and in the kidney. The RNA level increased about 10-fold during differentiation of F9 embryonal carcinoma cells to parietal endoderm cells

Subunit

Interacts with the LRP1/alpha-2-macroglobulin receptor heavy and light chains; the interaction is transient and coincides with a reduction of ligand binding by the receptor. Interacts with LRP2/glycoprotein 330. Interacts with LRP1B; binding is followed by internalization and degradation. Interacts with LDLR. Interacts with SORL1 (By similarity). Interacts with LRP1; this interaction is followed by rapid internalization (By similarity)

Gene: Lrpap1  |  Organism: Mus musculus  |  Synonyms: Heparin-binding protein 44; Low density lipoprotein receptor-related protein-associated protein 1

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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