Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial, Mus musculus (Mouse), Baculovirus, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 18.2kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial

Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial — recombinant protein from Mus musculus (Mouse), expressed in Baculovirus. Purity >85%.

SKU: BCRECP-003304 Category:
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Product Specifications

Product SkuBCRECP-003304
Product DescriptionRecombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1) Protein is expressed from Baculovirus with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 248-360aa. [Accession | P55302].
Uniprot No.P55302
Gene NamesLrpap1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region248-360aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight18.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasMetabolism

Function

Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.

Biological Context

Subcellular Location: Rough endoplasmic reticulum lumen; Endoplasmic reticulum-Golgi intermediate compartment lumen; Golgi apparatus, cis-Golgi network; Golgi apparatus lumen; Endosome lumen; Cell surface
Tissue Specificity: Highly expressed in PYS-2 parietal endoderm cells and in the kidney. The RNA level increased about 10-fold during differentiation of F9 embryonal carcinoma cells to parietal endoderm cells

Product Specifications

Recombinant Mouse Alpha-2-macroglobulin receptor-associated protein (Lrpap1), partial is a recombinant protein from Mus musculus (Mouse), expressed in Baculovirus, covering amino acids 248-360aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 18.2kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway

Subcellular Location

Rough endoplasmic reticulum lumen; Endoplasmic reticulum-Golgi intermediate compartment lumen; Golgi apparatus, cis-Golgi network; Golgi apparatus lumen; Endosome lumen; Cell surface

Tissue Specificity

Highly expressed in PYS-2 parietal endoderm cells and in the kidney. The RNA level increased about 10-fold during differentiation of F9 embryonal carcinoma cells to parietal endoderm cells

Subunit

Interacts with the LRP1/alpha-2-macroglobulin receptor heavy and light chains; the interaction is transient and coincides with a reduction of ligand binding by the receptor. Interacts with LRP2/glycoprotein 330. Interacts with LRP1B; binding is followed by internalization and degradation. Interacts with LDLR. Interacts with SORL1 (By similarity). Interacts with LRP1; this interaction is followed by rapid internalization (By similarity)

Gene: Lrpap1  |  Organism: Mus musculus  |  Synonyms: Heparin-binding protein 44; Low density lipoprotein receptor-related protein-associated protein 1

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

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Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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