Recombinant Mouse Annexin A2 (Anxa2) — recombinant protein from Mus musculus (Mouse), expressed in E.coli. Purity >90%.
| Product Sku | BCRECP-002099 |
| Product Description | Recombinant Mouse Annexin A2 (Anxa2) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 2-339aa. [Accession | P07356]. |
| Uniprot No. | P07356 |
| Gene Names | Anxa2 |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Expression System | E.coli |
| Expression Region | 2-339aa |
| Species | Mus musculus (Mouse) |
| Tag Info | N-terminal 10xHis-tagged and C-terminal Myc-tagged |
| Molecular weight | 46.0kDa |
| Activity | Please contact us to obtain bioactivity data. |
| Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose. |
| Storage | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| Research Areas | Signal Transduction |
(Microbial infection) Contributes to protection against Pseudomonas aeruginosa infection by regulating autophagy via the AKT1-mTOR-ULK1/2 signaling pathway and activation of Rho GTPases via FAM13A-mediated mechanism.
Recombinant Mouse Annexin A2 (Anxa2) — recombinant protein from Mus musculus (Mouse), expressed in E.coli. Purity >90%. Suitable for ELISA and Western Blot applications.
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Please contact us to obtain bioactivity data.
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
(Microbial infection) Contributes to protection against Pseudomonas aeruginosa infection by regulating autophagy via the AKT1-mTOR-ULK1/2 signaling pathway and activation of Rho GTPases via FAM13A-mediated mechanism
Early endosome
Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36 (By similarity). Interacts with ATP1B1 (By similarity). Interacts with DYSF (PubMed:14506282). Interacts with COCH. Interacts (via repeat Annexin 1) with PCSK9 (via the C-terminal domain); the interaction inhibits the degradation of LDLR. Interacts with CEACAM1 (via the cytoplasmic domain); this interaction is regulated by phosphorylation of CEACAM1 (By similarity). Interacts with APPL2 and APPL1; targets APPL2 to endosomes and acting in parallel to RAB5A (PubMed:21645192). Interacts with S100A4 (By similarity). May interact with UBAP2 (By similarity). Interacts with PLEKHG4B; this interaction is required for PLEKHG4B localization to cell-cell adhesions (By similarity). Interacts with FAM13A (PubMed:26371245). Interacts with salivary cystatin-L2 (via loop 2) from the tick Ixodes scapularis; the interaction results in reduced activation of mouse NLRC4 inflammasome formation upon Anaplasma phagocytophilum infection (PubMed:27045038)
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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.
Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.
Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.
Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.
