Recombinant Mouse Anti-Muellerian hormone (Amh), partial, Mus musculus (Mouse), E.coli, N-terminal 6xHis-tagged, 15.4kDa, purity >90% as determined by SDS-PAGE.

Recombinant Mouse Anti-Muellerian hormone (Amh), partial

Recombinant Mouse Anti-Muellerian hormone (Amh), partial — Plays an important role in several reproductive functions, including Muellerian duct regression during male fetal sexua,l differentiation and in the adult plays a role in Leydig cell differentiatio… Purity >90%.

SKU: BCRECP-002076 Category:
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Product Specifications

Product SkuBCRECP-002076
Product DescriptionRecombinant Mouse Anti-Muellerian hormone (Amh) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 450-552aa. [Accession | P27106].
Uniprot No.P27106
Gene NamesAmh
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region450-552aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-tagged
Molecular weight15.4kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Plays an important role in several reproductive functions, including Muellerian duct regression during male fetal sexua,l differentiation and in the adult plays a role in Leydig cell differentiation and function. In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles.

Product Specifications

Recombinant Mouse Anti-Muellerian hormone (Amh), partial — Plays an important role in several reproductive functions, including Muellerian duct regression during male fetal sexua,l differentiation and in the adult plays a role in Leydig cell differentiatio… Purity >90%. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Plays an important role in several reproductive functions, including Muellerian duct regression during male fetal sexua,l differentiation and in the adult plays a role in Leydig cell differentiation and function (PubMed:1782869, PubMed:9435237). In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles (PubMed:11606457, PubMed:11861535). Binds to its sole type II receptor, AMHR2 that recruits type I receptors ACVR1 and BMPR1A which subsequently activates the Smad pathway (By similarity)

Subcellular Location

Secreted

Tissue Specificity

Expressed in Sertoli cells of fetal testes, and in testes just after birth, but absent in adult testes. In female, AMH is expressed after birth in the granulosa cells of the follicle

Subunit

Homodimer; disulfide-linked (By similarity). Anti-Muellerian hormone (AMH) is secreted as part of a non-covalent heterotetrameric complex consisting of AMH prodomain and anti-Muellerian hormone homodimers (By similarity). After proteolytic processing, the dimeric AMH prodomain remains non-covalently associated with the active homodimeric anti-Muellerian hormone, amplifying its biological activity (By similarity). The AMH prodomain homodimer is displaced upon binding of anti-Muellerian hormone to its receptor (By similarity)

Gene: Amh  |  Organism: Mus musculus  |  Synonyms: Muellerian-inhibiting factor; Muellerian-inhibiting substance
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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