Recombinant Mouse C-X-C chemokine receptor type 3 (Cxcr3), partial, Mus musculus (Mouse), E.coli, N-terminal 6xHis-KSI-tagged, 21.3kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Mouse C-X-C chemokine receptor type 3 (Cxcr3), partial

Recombinant Mouse C-X-C chemokine receptor type 3 (Cxcr3), partial — Receptor for the C-X-C chemokines CXCL9, CXCL10 and CXCL11, and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G protein signaling pathway. Purity >85%.

SKU: BCRECP-002487 Categories: ,
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Product Specifications

Product SkuBCRECP-002487
Product DescriptionRecombinant Mouse C-X-C chemokine receptor type 3 (Cxcr3) Protein is expressed from E.coli with N-terminal 6xHis-KSI-tagged. It contains 1-52aa. [Accession | O88410].
Uniprot No.O88410
Gene NamesCxcr3
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-52aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-KSI-tagged
Molecular weight21.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

Receptor for the C-X-C chemokines CXCL9, CXCL10 and CXCL11, and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G protein signaling pathway. Probably promotes cell chemotaxis response. Receptor for chemokine CCL21.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)
Tissue Specificity: Expresses in lymphoid organs and Th1 cells

Product Specifications

Recombinant Mouse C-X-C chemokine receptor type 3 (Cxcr3), partial is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 1-52aa, with N-terminal 6xHis-KSI-tagged tag, molecular weight 21.3kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Receptor for the C-X-C chemokines CXCL9, CXCL10 and CXCL11, and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G protein signaling pathway. Probably promotes cell chemotaxis response (By similarity). Receptor for chemokine CCL21 (PubMed:10201891, PubMed:9653165). Upon activation by PF4, induces activated T-lymphocyte migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Tissue Specificity

Expresses in lymphoid organs and Th1 cells

Subunit

Homomer. Forms heteromers with ACKR4 (By similarity). Interacts with PF4/CXCL4 (By similarity)

Gene: Cxcr3  |  Organism: Mus musculus  |  Synonyms: Interferon-inducible protein 10 receptor

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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