Function
Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli.
Biological Context
Subcellular Location: Cell membrane (Single-pass type I membrane protein)
Tissue Specificity: Expressed in granulocytes, monocytes, most T-cells and a subset of NK, NKT and B-cells (at protein level). Expressed in the spleen, lung, liver, testis, bone marrow, lymph nodes, spinal cord, kidney, uterus and small intestine. Expressed in mast and dendritic cells. Expressed in the lung of N.brasiliensis-infected mice
Product Specifications
Recombinant Mouse Cell surface glycoprotein CD200 receptor 1 (Cd200r1), partial, Biotinylated is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 26-238aa, with N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged tag, molecular weight 73.5kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications. Explore more Biotinylated proteins →
