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Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B)

Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) — Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. Purity >95%.

SKU: BCRETP-000017 Categories: ,

Product Specifications

Product SkuBCRETP-000017
Product DescriptionEukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) is expressed from HEK293 with His tag at the N-Terminus. It contains 23-258aa. [Accession | P25119].
Uniprot No.P25119
SynonymsCD120b Protein, Mouse;p75 Protein, Mouse;TNF-alphaR2 Protein, Mouse;TNF-R-II Protein, Mouse;TNF-R2 Protein, Mouse;TNF-R75 Protein, Mouse;TNFalpha-R2 Protein, Mouse;TNFBR Protein, Mouse;Tnfr-1 Protein, Mouse;Tnfr2 Protein, Mouse;TNFR80 Protein, Mouse;TNFRI
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemHEK293 Cells
Expression Region23-258aa
Tag InfoN-6His
Molecular weight46-50kDa
EndotoxinLess than 1.0 EU/μg as determined by LAL method.

Function

Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

Product Specifications

Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) is a recombinant protein, expressed in HEK293 Cells, covering amino acids 23-258aa, with N-6His tag, molecular weight 46-50kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 (By similarity)

Gene: Tnfrsf1b  |  Organism: Mus musculus

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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