Recombinant Mouse Complement C1s-B subcomponent (C1sb), Mus musculus (Mouse), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 82.4kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Complement C1s-B subcomponent (C1sb)

Recombinant Mouse Complement C1s-B subcomponent (C1sb) — Serine protease component of the complement C1 complex, which catalyzes cleavage and activation of C2 and C4, the next components of the classical complement pathway. Purity >85%.

SKU: BCRECP-002270 Category:
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Product Specifications

Product SkuBCRECP-002270
Product DescriptionRecombinant Mouse Complement C1s-B subcomponent (C1sb) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 16-688aa. [Accession | Q8CFG8].
Uniprot No.Q8CFG8
Gene NamesC1sb
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region16-688aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight82.4kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Serine protease component of the complement C1 complex, which catalyzes cleavage and activation of C2 and C4, the next components of the classical complement pathway. Also cleaves IGFBP5 and thereby inhibits the trophic effects of IGF1.

Biological Context

Subcellular Location: Secreted; Cell surface
Tissue Specificity: Specifically expressed in male reproductive tissues

Product Specifications

Recombinant Mouse Complement C1s-B subcomponent (C1sb) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 16-688aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 82.4kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Serine protease component of the complement C1 complex, which catalyzes cleavage and activation of C2 and C4, the next components of the classical complement pathway. Also cleaves IGFBP5 and thereby inhibits the trophic effects of IGF1

Subcellular Location

Secreted; Cell surface

Tissue Specificity

Specifically expressed in male reproductive tissues

Subunit

Core component of the complement C1 complex, a calcium-dependent complex composed of 1 molecule of the C1Q subcomplex, 2 molecules of C1R and 2 molecules of C1S. The C1Q subcomplex is composed 18 subunits: 3 chains of C1QA, C1QB, and C1QC trimerize to form 6 collagen-like triple helices connected to six globular ligand-recognition modules

Gene: C1s2  |  Organism: Mus musculus  |  Synonyms: C1 esterase; Complement C1s-B subcomponent; Complement component 1 subcomponent s-B; Complement component 1, S subcomponent 2

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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