Recombinant Mouse Delta-like protein 3 (Dll3), partial (Active), Mus musculus (Mouse), Mammalian cell, N-terminal HSA-tagged and C-terminal 10xHis-tagged, 115.7 kDa, purity >95% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.

Recombinant Mouse Delta-like protein 3 (Dll3), partial (Active)

Recombinant Mouse Delta-like protein 3 (Dll3), partial (Active) — Inhibits primary neurogenesis. Purity >95%.

SKU: BCACP-000643 Category:
Online Inquiry →
Product SKUBCACP-000643
Product DescriptionRecombinant Mouse Delta-like protein 3 (Dll3) protein is expressed from Mammalian cell with N-terminal HSA-tagged and C-terminal 10xHis-tagged. It contains 33-490aa. [Accession | O88516].
Uniprot No.O88516
Gene NamesDll3
PurityGreater than 95% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region33-490aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal HSA-tagged and C-terminal 10xHis-tagged
Molecular weight115.7 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human CCN2 at 1 μg/mL can bind Anti-CCN2 recombinant antibody . The EC50 is 0.7088-0.8299 ng/mL.;CCN2 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Recombinant Human CCN2 with an affinity constant of 6.43 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesDelta-like protein 3; Drosophila Delta homolog 3; Delta3; M-Delta-3

Function

Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)
Tissue Specificity: Predominantly expressed in the neuroectoderm and paraxial mesoderm during embryogenesis
Disease Association: [A truncating mutation in Dll3 is the cause of the pudgy (pu) phenotype. Pudgy mice exhibit patterning defects at the earliest stages of somitogenesis. Adult pudgy mice present severe vertebral and rib deformities]

Product Specifications

Recombinant Mouse Delta-like protein 3 (Dll3), partial (Active) is a recombinant protein from Mus musculus (Mouse), expressed in Mammalian cell, covering amino acids 33-490aa, with N-terminal HSA-tagged and C-terminal 10xHis-tagged tag, molecular weight 115.7 kDa, purity Greater than 95% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CCN2 at 1 μg/mL can bind Anti-CCN2 recombinant antibody . The EC50 is 0.7088-0.8299 ng/mL.;CCN2 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Recombinant Human CCN2 with an affinity constant of 6.43 nM as detected by MetaSPR Assay (WeSPRTM 200).

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm

Subcellular Location

Membrane (Single-pass type I membrane protein)

Disease Association

[A truncating mutation in Dll3 is the cause of the pudgy (pu) phenotype. Pudgy mice exhibit patterning defects at the earliest stages of somitogenesis. Adult pudgy mice present severe vertebral and rib deformities]

Tissue Specificity

Predominantly expressed in the neuroectoderm and paraxial mesoderm during embryogenesis

Subunit

Can bind and activate Notch-1 or another Notch receptor

Gene: Dll3  |  Organism: Mus musculus  |  Synonyms: Drosophila Delta homolog 3

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top