Recombinant Mouse EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1), Mus musculus (Mouse), Yeast, N-terminal 6xHis-tagged, 55.0kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Mouse EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1)

Recombinant Mouse EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1) — Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. Purity >90%.

SKU: BCRECP-002592 Categories: ,
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Product Specifications

Product SkuBCRECP-002592
Product DescriptionRecombinant Mouse EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1) Protein is expressed from Yeast with N-terminal 6xHis-tagged. It contains 18-493aa. [Accession | Q8BPB5].
Uniprot No.Q8BPB5
Gene NamesEfemp1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region18-493aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-tagged
Molecular weight55.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration.

Product Specifications

Recombinant Mouse EGF-containing fibulin-like extracellular matrix protein 1 (Efemp1) — Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. Purity >90%. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth (By similarity)

Subcellular Location

Secreted, extracellular space, extracellular matrix

Tissue Specificity

Expressed in the eye in the ciliary body, cornea, inner nuclear layer of the retina, and in the optic disk

Subunit

Interacts with ECM1. Interacts with TIMP3

Gene: Efemp1  |  Organism: Mus musculus  |  Synonyms: Fibulin-3
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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